Novel carbazole-triazole conjugates as DNA-targeting membrane active potentiators against clinical isolated fungi

A series of carbazole-triazole conjugates were designed, synthesized and characterized by IR, NMR, and HRMS spectra. Biological assay showed that most of the synthesized compounds exhibited moderate and even strong antifungal activities, especially 3,6-dibromocarbazolyl triazole 5d displayed excelle...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	European journal of medicinal chemistry 2018-07, Vol.155, p.579-589
Hauptverfasser:	Zhang, Yuan, Tangadanchu, Vijai Kumar Reddy, Bheemanaboina, Rammohan R. Yadav, Cheng, Yu, Zhou, Cheng-He
Format:	Artikel
Sprache:	eng
Schlagworte:	Antifungal Carbazole DNA Resistance Triazole
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!