Chronic exposure to fungicide propamocarb induces bile acid metabolic disorder and increases trimethylamine in C57BL/6J mice

Propamocarb (PM) is a widely used fungicide that affects lipid biosynthesis in fungi. In this study, we explored the effects of PM on mouse metabolism and gut microbiota-related pathways by exposing C57BL/6J mice to 1, 3, and 10 mg/L PM through drinking water for a duration of 10 weeks. We found tha...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	The Science of the total environment 2018-11, Vol.642, p.341-348
Hauptverfasser:	Wu, Sisheng, Luo, Ting, Wang, Siyu, Zhou, Jicong, Ni, Yingchun, Fu, Zhengwei, Jin, Yuanxiang
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bile acids Bile Acids and Salts - metabolism Carbamates - toxicity Energy metabolism Gut microbiota Liver Metabolic Diseases - chemically induced Methylamines - metabolism Mice Mice, Inbred C57BL Propamocarb Toxicity Tests Trimethylamine
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!