Visfatin alters the cytokine and matrix-degrading enzyme profile during osteogenic and adipogenic MSC differentiation

Age-related bone loss is associated with bone marrow adiposity. Adipokines (e.g., visfatin, resistin, leptin) are adipocyte-derived factors with immunomodulatory properties and might influence differentiation of bone marrow-derived mesenchymal stem cells (MSC) in osteoarthritis (OA) and osteoporosis...

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Veröffentlicht in:	Osteoarthritis and cartilage 2018-09, Vol.26 (9), p.1225-1235
Hauptverfasser:	Tsiklauri, L., Werner, J., Kampschulte, M., Frommer, K.W., Berninger, L., Irrgang, M., Glenske, K., Hose, D., El Khassawna, T., Pons-Kühnemann, J., Rehart, S., Wenisch, S., Müller-Ladner, U., Neumann, E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipogenesis Adipokines Fragility fracture Mesenchymal stem cell Osteoarthritis Osteogenesis Osteoporosis
Online-Zugang:	Volltext
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