The classification of pediatric and young adult renal cell carcinomas registered on the children's oncology group (COG) protocol AREN03B2 after focused genetic testing

BACKGROUND Renal cell carcinomas (RCCs) are rare in young patients. Knowledge of their pathologic and molecular spectrum remains limited, and no prospective studies have been performed to date in this population. This study analyzes patients diagnosed with RCC who were prospectively enrolled in the...

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Veröffentlicht in:	Cancer 2018-08, Vol.124 (16), p.3381-3389
Hauptverfasser:	Cajaiba, Mariana M., Dyer, Lisa M., Geller, James I., Jennings, Lawrence J., George, David, Kirschmann, Dawn, Rohan, Stephen M., Cost, Nicholas G., Khanna, Geetika, Mullen, Elizabeth A., Dome, Jeffrey S., Fernandez, Conrad V., Perlman, Elizabeth J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Children Classification Clear cell-type renal cell carcinoma Diagnostic systems Fumarase Genetic screening Kidney cancer Kinases Lymphoma Occupational health Oncology Patients pediatric renal tumor Population studies Protein-tyrosine kinase renal cell carcinoma Succinate dehydrogenase Thyroid transcription factor E3 (TFE3) gene transcription factor EB (TFEB) gene Transcription factors Translocation translocation renal cell carcinoma Tuberous sclerosis Tumors
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