Hydroxamic Acid-Containing Hydrogels for Nonabsorbed Iron Chelation Therapy: Synthesis, Characterization, and Biological Evaluation
Iron overload is a severe clinical condition and can be largely prevented by the use of iron-specific chelating agents. A successful iron chelator needs to be orally active, nontoxic, and selective. In this study, hydrogels containing pendant hydroxamic acid groups have been synthesized as potential...
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Veröffentlicht in: | Biomacromolecules 2005-11, Vol.6 (6), p.2946-2953 |
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Format: | Artikel |
Sprache: | eng |
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