In vivo confocal microscopy, an inner vision of the cornea - a major review
The demands of modern ophthalmology have evolved from descriptive findings from the slit lamp to in vivo assessment of cellular level changes. Nowadays, the latter can be provided by in vivo confocal microscopy. This article gives an overview of confocal principles using tandem scanning, scanning sl...
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Veröffentlicht in: | Clinical & experimental ophthalmology 2009-01, Vol.37 (1), p.100-117 |
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creator | Guthoff, Rudolf F Zhivov, Andrey Stachs, Oliver |
description | The demands of modern ophthalmology have evolved from descriptive findings from the slit lamp to in vivo assessment of cellular level changes. Nowadays, the latter can be provided by in vivo confocal microscopy. This article gives an overview of confocal principles using tandem scanning, scanning slit and laser scanning techniques used in ophthalmology. The main part of the paper describes the clinical applications emphasizing the anatomy of the normal and pathological cornea, and illustrates side‐effects of topical medication, contact lens wear, cross‐linking and refractive surgery. Finally, a summary about experimental applications, including animal studies, surface characterization and volume rendering as well as future developments, is given. |
doi_str_mv | 10.1111/j.1442-9071.2009.02016.x |
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Finally, a summary about experimental applications, including animal studies, surface characterization and volume rendering as well as future developments, is given.</description><subject>Administration, Topical</subject><subject>Animals</subject><subject>confocal microscopy</subject><subject>Contact Lenses - adverse effects</subject><subject>cornea</subject><subject>Cornea - anatomy & histology</subject><subject>Cornea - drug effects</subject><subject>Cornea - pathology</subject><subject>Corneal Diseases - pathology</subject><subject>Diagnosis, Differential</subject><subject>Humans</subject><subject>laser scanning</subject><subject>Microscopy, Confocal - classification</subject><subject>Microscopy, Confocal - methods</subject><subject>Microscopy, Confocal - trends</subject><subject>Mitomycin - administration & dosage</subject><subject>Mitomycin - adverse effects</subject><subject>Nucleic Acid Synthesis Inhibitors - administration & dosage</subject><subject>Nucleic Acid Synthesis Inhibitors - adverse effects</subject><subject>Postoperative Care</subject><subject>Preservatives, Pharmaceutical - adverse effects</subject><subject>Pterygium - surgery</subject><subject>Refractive Surgical Procedures - adverse effects</subject><issn>1442-6404</issn><issn>1442-9071</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkE1vEzEQhi0EoqXtX0A-cWKX8ed6DxwgKqFQUQlBerSc3VnhsLsOdpIm_75eEpUrvniked6x5yGEMihZPu9WJZOSFzVUrOQAdQkcmC73z8j5U-P5qdYS5Bl5ldIKABQX-iU5Y7UQRoM5J19vRrrzu0CbMHahcT0dfBNDasL68Ja6kfpxxJiR5MNIQ0c3vzCzcURHC-ro4FYh0og7jw-X5EXn-oRXp_uC_Px0_WP2ubi9m9_MPtwWjVJcF21rqvwnqdzScNfUNZdYI2qFlRGgkVWoQIi25krqtkOQrAMljKyX0gltxAV5c5y7juHPFtPGDj412PduxLBNloPSOSQyaI7gtFGK2Nl19IOLB8vATiLtyk6O7OTLTiLtX5F2n6OvT29slwO2_4Incxl4fwQefI-H_x5sZ9d3U5XzxTHv0wb3T3kXf1tdiUrZ-29za2CxmH__uLBfxCN2Po50</recordid><startdate>200901</startdate><enddate>200901</enddate><creator>Guthoff, Rudolf F</creator><creator>Zhivov, Andrey</creator><creator>Stachs, Oliver</creator><general>Blackwell Publishing Asia</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope></search><sort><creationdate>200901</creationdate><title>In vivo confocal microscopy, an inner vision of the cornea - a major review</title><author>Guthoff, Rudolf F ; 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subjects | Administration, Topical Animals confocal microscopy Contact Lenses - adverse effects cornea Cornea - anatomy & histology Cornea - drug effects Cornea - pathology Corneal Diseases - pathology Diagnosis, Differential Humans laser scanning Microscopy, Confocal - classification Microscopy, Confocal - methods Microscopy, Confocal - trends Mitomycin - administration & dosage Mitomycin - adverse effects Nucleic Acid Synthesis Inhibitors - administration & dosage Nucleic Acid Synthesis Inhibitors - adverse effects Postoperative Care Preservatives, Pharmaceutical - adverse effects Pterygium - surgery Refractive Surgical Procedures - adverse effects |
title | In vivo confocal microscopy, an inner vision of the cornea - a major review |
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