Synthesis and activity of a diselenide bond mimetic of the antimicrobial protein caenopore-5

Antimicrobial proteins are a rich source of new lead compounds for the development of new drugs that will tackle global resistance towards existing antibiotics. Caenopore-5 ( Cp-5 ) is an antimicrobial protein (AMP) expressed in the intestine of the nematode Caenorhabditis elegans and is a member of...

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Veröffentlicht in:	Chemical science (Cambridge) 2016-03, Vol.7 (3), p.25-21
Hauptverfasser:	Medini, Karima, Harris, Paul. W. R, Menorca, Ayana, Hards, Kiel, Cook, Gregory. M, Brimble, Margaret. A
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiinfectives and antibacterials Binding Bonding Caenorhabditis Chemistry Dichroism Drugs Nematoda Nematodes Peptides Proteins
Online-Zugang:	Volltext
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