Response to long-term lamivudine treatment in patients infected with hepatitis B virus genotypes A, B, and C

Response to lamivudine treatment longer than 1 year was compared in 15 patients persistently infected with hepatitis B virus (HBV) genotype A, 38 with genotype B, and 449 with genotype C. Patients with genotype A were younger (median age 37 [range 24–49] vs. 47 [24–67] or 44 [18–73], P = 0.015), pos...

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Veröffentlicht in:	Journal of medical virology 2006-10, Vol.78 (10), p.1276-1283
Hauptverfasser:	Kobayashi, Mariko, Suzuki, Fumitaka, Akuta, Norio, Suzuki, Yoshiyuki, Arase, Yasuji, Ikeda, Kenji, Hosaka, Tetsuya, Sezaki, Hitomi, Kobayashi, Masahiro, Iwasaki, Satomi, Sato, Junko, Watahiki, Sachiyo, Miyakawa, Yuzo, Kumada, Hiromitsu
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adolescent Adult Aged Biological and medical sciences chronic hepatitis cirrhosis Disease Progression Female Fundamental and applied biological sciences. Psychology Genetic Markers Genome, Viral Genotype genotypes Hepatitis B virus Hepatitis B virus - classification Hepatitis B virus - drug effects Hepatitis B virus - genetics Hepatitis B, Chronic - diagnosis Hepatitis B, Chronic - drug therapy Hepatitis B, Chronic - virology Hospitals, Urban Human viral diseases Humans Infectious diseases lamivudine Lamivudine - administration & dosage Lamivudine - adverse effects Lamivudine - pharmacology Lamivudine - therapeutic use Male Medical sciences Microbiology Middle Aged Miscellaneous Mutation Proportional Hazards Models Reverse Transcriptase Inhibitors - administration & dosage Reverse Transcriptase Inhibitors - adverse effects Reverse Transcriptase Inhibitors - therapeutic use Time Factors Tokyo Treatment Outcome Viral diseases Viral hepatitis Virology
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