Resuscitation with Lipid versus Epinephrine in a Rat Model of Bupivacaine Overdose

Lipid emulsion infusion reverses cardiovascular compromise due to local anesthetic overdose in laboratory and clinical settings. The authors compared resuscitation with lipid, epinephrine, and saline control in a rat model of bupivacaine-induced cardiac toxicity to determine whether lipid provides a...

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Veröffentlicht in:	Anesthesiology (Philadelphia) 2008-05, Vol.108 (5), p.907-913
Hauptverfasser:	WEINBERG, Guy L, DI GREGORIO, Guido, RIPPER, Richard, KELLY, Kemba, MASSAD, Malek, EDELMAN, Lucas, SCHWARTZ, David, SHAH, Nirali, ZHENG, Sophie, FEINSTEIN, Douglas L
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Anesthetics, Local - therapeutic use Anesthetics, Local - toxicity Animals Biological and medical sciences Bupivacaine - administration & dosage Bupivacaine - therapeutic use Bupivacaine - toxicity Disease Models, Animal Drug Overdose - prevention & control Epinephrine - pharmacology Heart - drug effects Infusions, Intravenous Lipids - therapeutic use Male Medical sciences Rats Rats, Sprague-Dawley Resuscitation - methods
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