Relation between rotation in the 6-OHDA lesioned rat and dopamine loss in striatal and substantia nigra subregions

The relation between the rotation response to drug‐induced activation of the dopamine (DA) receptor in the rat unilaterally lesioned with 6‐hydroxydopamine (6‐OHDA) in the substantia nigra (SN) and the loss of DA in subregions of the SN and caudate‐putamen (C/PUT) is not clear. Here this relation wa...

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Veröffentlicht in:	Synapse (New York, N.Y.) N.Y.), 2006-06, Vol.59 (8), p.532-544
Hauptverfasser:	Olds, M.E., Jacques, D.B., Kopyov, O.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amphetamine - pharmacology Animals Caudate Nucleus - drug effects Caudate Nucleus - metabolism Corpus Striatum - drug effects Corpus Striatum - metabolism DA loss Dopamine - metabolism Male Motor Activity - drug effects Motor Activity - physiology Nucleus Accumbens - drug effects Nucleus Accumbens - metabolism Oxidopamine - toxicity Putamen - drug effects Putamen - metabolism Rats Rotation striatal subregions Substantia Nigra - drug effects Substantia Nigra - metabolism Tyrosine 3-Monooxygenase - metabolism
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