FAD24 Acts in Concert with Histone Acetyltransferase HBO1 to Promote Adipogenesis by Controlling DNA Replication

Preadipocytes differentiate into adipocytes through approximately two rounds of mitosis, referred to as mitotic clonal expansion (MCE), but the events early in the differentiation process are not fully understood. Previously, we identified and characterized a novel gene, fad24 (factor for adipocyte...

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Veröffentlicht in:	The Journal of biological chemistry 2008-01, Vol.283 (4), p.2265-2274
Hauptverfasser:	Johmura, Yoshikazu, Osada, Shigehiro, Nishizuka, Makoto, Imagawa, Masayoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells Adipocytes - cytology Adipocytes - metabolism Adipogenesis - drug effects Adipogenesis - physiology Animals Basic-Leucine Zipper Transcription Factors - antagonists & inhibitors Basic-Leucine Zipper Transcription Factors - genetics Basic-Leucine Zipper Transcription Factors - metabolism Cell Cycle Proteins Cell Differentiation - drug effects Cell Differentiation - physiology Chromatin - genetics Chromatin - metabolism DNA Replication - drug effects DNA Replication - physiology Gene Expression Regulation - drug effects Gene Expression Regulation - physiology Gene Silencing Histone Acetyltransferases - genetics Histone Acetyltransferases - metabolism Mice Mitosis - drug effects Mitosis - physiology Nuclear Proteins - antagonists & inhibitors Nuclear Proteins - genetics Nuclear Proteins - metabolism Origin Recognition Complex - genetics Origin Recognition Complex - metabolism Replication Origin - physiology RNA, Small Interfering - genetics RNA, Small Interfering - pharmacology
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