Oligomeric Structure and Three-Dimensional Fold of the HIV gp41 Membrane-Proximal External Region and Transmembrane Domain in Phospholipid Bilayers

The HIV-1 glycoprotein, gp41, mediates fusion of the virus lipid envelope with the target cell membrane during virus entry into cells. Despite extensive studies of this protein, inconsistent and contradictory structural information abounds in the literature about the C-terminal membrane-interacting...

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Veröffentlicht in:	Journal of the American Chemical Society 2018-07, Vol.140 (26), p.8246-8259
Hauptverfasser:	Kwon, Byungsu, Lee, Myungwoon, Waring, Alan J, Hong, Mei
Format:	Artikel
Sprache:	eng
Schlagworte:	HIV Envelope Protein gp41 - chemistry Lipid Bilayers - chemistry Phospholipids - chemistry Protein Conformation Protein Folding
Online-Zugang:	Volltext
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