Inhalation of repurposed drugs to treat pulmonary hypertension

Pulmonary arterial hypertension (PAH) is a rare, but severe and life-threatening disease characterized by vasoconstriction and remodeling of the pulmonary arterioles, leading to progressive increase in pulmonary vascular resistance and ultimately to right-heart failure. In the last two decades, sign...

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Veröffentlicht in:	Advanced drug delivery reviews 2018-08, Vol.133, p.34-44
1. Verfasser:	Gessler, Tobias
Format:	Artikel
Sprache:	eng
Schlagworte:	Aerosol therapy Inhalation Inhaled iloprost Inhaled treprostinil Prostacyclin analogues Pulmonary arterial hypertension Pulmonary selectivity Repurposed drugs Vascular remodeling
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