Reversal of akinesia in experimental parkinsonism by GABA antagonist microinjections in the pedunculopontine nucleus

Recent studies, mainly in animals, have shown that the pedunculopontine nucleus (PPN) in the upper brainstem has extensive connections with several motor centres in the CNS. This structure has also been implicated in the akinesia seen in patients with Parkinson’s disease. Here we demonstrate that mi...

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Veröffentlicht in:Brain (London, England : 1878) England : 1878), 2002-11, Vol.125 (11), p.2418-2430
Hauptverfasser: Nandi, Dipankar, Aziz, Tipu Z., Giladi, Nir, Winter, Jonathan, Stein, John F.
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Sprache:eng
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