ORMDL3 and its implication in inflammatory disorders

A growing body of evidence has suggested the genetic association of ORMDL3 gene (ORMDL Sphingolipid Biosynthesis Regulator 3) polymorphisms with a diverse set of inflammatory disorders that include bronchial asthma, inflammatory bowel disease, ankylosing spondylitis and atherosclerosis. Gene functio...

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Veröffentlicht in:	International journal of rheumatic diseases 2018-06, Vol.21 (6), p.1154-1162
Hauptverfasser:	Ma, Xiaochun, Long, Feng, Yun, Yan, Dang, Jie, Wei, Shijun, Zhang, Qian, Li, Jinzhang, Zhang, Haizhou, Zhang, Wenlong, Wang, Zhengjun, Liu, Qiji, Zou, Chengwei
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Ankylosing spondylitis Apoptosis Arteriosclerosis Asthma autophagy Autophagy - genetics Endoplasmic reticulum endoplasmic reticulum stress Endoplasmic Reticulum Stress - genetics Gene expression Gene Expression Regulation Genetic Association Studies Genetic Predisposition to Disease Humans inflammation Inflammation - genetics Inflammation - metabolism Inflammation - pathology Inflammatory bowel diseases Inflammatory diseases Intestine Lipid metabolism Lipid Metabolism - genetics Membrane Proteins - genetics Membrane Proteins - metabolism ORMDL3 Phenotype polymorphism Polymorphism, Genetic Risk Factors Spondylitis Transcription, Genetic
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