Adipose-Derived Stem Cells in a Resilient In Situ Forming Hydrogel Modulate Macrophage Phenotype

Injectable hydrogels have the potential to enhance stem cell-based therapies by improving cell localization, retention, and survival after transplantation. The inflammatory response to both the hydrogel and the encapsulated cells is a critical aspect of this strategy, with macrophages being highly i...

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Veröffentlicht in:	Tissue engineering. Part A 2018-12, Vol.24 (23-24), p.1784-1797
Hauptverfasser:	Young, Stuart A., Flynn, Lauren E., Amsden, Brian G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Arginase Biomedical materials CCR7 protein CD163 antigen Cell survival Chemical engineering Genotype & phenotype Hydrogels Immunomodulation Inflammation Injection Ischemia Localization Macrophages Nitric oxide Nitric-oxide synthase Original Articles Peptides Phenotypes Retention Stem cell transplantation Stem cells Stromal cells Transplants & implants
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