Hydrophilic interaction chromatography coupled to tandem mass spectrometry as a method for simultaneous determination of guanidinoacetate and creatine

The biosynthesis of creatine (Cr) is closely related to the bioavailability of guanidinoacetate (GAA). The lack of one or the other may compromise their role in the energy transport and cell signaling. A reliable estimate of their levels in biological samples is imperative since they are important m...

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Veröffentlicht in:Analytica chimica acta 2018-10, Vol.1028, p.96-103
Hauptverfasser: Jovanov, Pavle, Vraneš, Milan, Sakač, Marijana, Gadžurić, Slobodan, Panić, Jovana, Marić, Aleksandar, Ostojić, Sergej
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Sprache:eng
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