Maturation of coordinated immediate early gene expression by cocaine during adolescence

Abstract Adolescence may be a critical period for drug addiction. Young adolescent male rats have greater locomotor responses than adults after acute low dose cocaine administration. Further, repeated cocaine administration produces as much or more conditioned place preference but reduced locomotor...

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Veröffentlicht in:	Neuroscience 2009-04, Vol.160 (1), p.13-31
Hauptverfasser:	Caster, J.M, Kuhn, C.M
Format:	Artikel
Sprache:	eng
Schlagworte:	adolescence Analysis of Variance Animals Autoradiography Biological and medical sciences Brain - drug effects Brain - growth & development c-fos Cerebral Cortex - drug effects Cerebral Cortex - growth & development cocaine Cocaine - administration & dosage Corpus Striatum - drug effects Corpus Striatum - growth & development Dopamine Uptake Inhibitors - administration & dosage Early Growth Response Protein 1 - genetics Early Growth Response Protein 1 - metabolism Fundamental and applied biological sciences. Psychology Gene Expression - drug effects Genes, Immediate-Early - drug effects In Situ Hybridization locomotion Male Medical sciences Motor Activity - drug effects Neurology Neurons - drug effects Neurons - physiology Neuropharmacology Pharmacology. Drug treatments Proto-Oncogene Proteins c-fos - genetics Proto-Oncogene Proteins c-fos - metabolism Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psychology. Psychoanalysis. Psychiatry Psychopharmacology rat Rats Rats, Sprague-Dawley Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - metabolism Vertebrates: nervous system and sense organs zif268
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