Protracted cognitive effects produced by clonidine in Macaca nemestrina performing a delayed matching task

Introduction The α 2 -adrenergic receptor agonist clonidine was examined for its ability to improve working memory in monkeys. Materials and methods Clonidine (0.116–34.8 μg/kg) was administered to six pigtail macaques in their performance of a computer-assisted delayed matching-to-sample (DMTS) tas...

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Veröffentlicht in:	Psychopharmacology 2009, Vol.202 (1-3), p.477-485
Hauptverfasser:	Buccafusco, Jerry J., Webster, Scott J., Terry, Alvin V., Kille, Nancy, Blessing, Donna
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic alpha-Agonists - pharmacology Animals Biomedical and Life Sciences Biomedicine Clonidine - pharmacology Cognition & reasoning Cognition - drug effects Dose-Response Relationship, Drug Female Macaca nemestrina Male Memory Memory - drug effects Memory, Short-Term - drug effects Monkeys & apes Neurosciences Original Investigation Pharmacology Pharmacology/Toxicology Psychiatry Psychomotor Performance - drug effects Psychotropic drugs
Online-Zugang:	Volltext
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