Prolonged and severe thrombocytopenia with pancytopenia induced by radiation-combined temozolomide therapy in a patient with newly diagnosed glioblastoma—analysis of O 6-methylguanine-DNA methyltransferase status

We report a case of a 51-year-old woman with newly diagnosed glioblastoma multiforme (GBM) who was treated with surgery followed by the standard concomitant temozolomide (TMZ) and radiotherapy (RT). Although TMZ is generally safe and well-tolerated, she developed a sudden onset of prolonged and seve...

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Veröffentlicht in:	Journal of neuro-oncology 2009-04, Vol.92 (2), p.227-232
Hauptverfasser:	Nagane, Motoo, Nozue, Kyoko, Shimizu, Saki, Waha, Andreas, Miyazaki, Hiroshi, Kurita, Hiroki, Homori, Masashi, Fujioka, Yasunori, Shiokawa, Yoshiaki
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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