Identification and characterization of reaction products of 5‐hydroxytryptamine with methylglyoxal and glyoxal by liquid chromatography/tandem mass spectrometry

Rationale Methylglyoxal (MGO) and glyoxal (GO) are known to be at high levels in humans with diabetes. They react with amine‐containing proteins and amino acids to form advanced glycation end products, however, their reactivity with other amine‐containing metabolites, such as neurotransmitters, has...

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Veröffentlicht in:	Rapid communications in mass spectrometry 2018-09, Vol.32 (17), p.1529-1539
Hauptverfasser:	Sai Sachin, L., Nagarjuna Chary, R., Pavankumar, P., Prabhakar, S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Columns (structural) Diabetes Liquid chromatography Mass spectrometers Mass spectrometry Metabolites Neurotransmitters Physiology Proteins Quadrupoles Reaction products Spectrometers
Online-Zugang:	Volltext
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