Rapid purification of billions of circulating CD19+ B cells directly from leukophoresis samples

•Purification of large numbers of CD19+ B cells directly from leukophoresis samples.•Excellent source of V genes to create in vitro antibody repertoires or study humoral immune responses.•Unbiased enrichment of natural B cell subpopulations. The study of the biology and function of B cells, or the d...

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Veröffentlicht in:	New biotechnology 2018-11, Vol.46, p.14-21
Hauptverfasser:	Ferrara, Fortunato, Kolnik, Martin, D’Angelo, Sara, Erasmus, Frank M., Vorholt, Daniela, Bradbury, Andrew R.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	B cells Biotechnology CD19 antigen Cells Flow cytometry Immunoglobulins Leukapheresis Lymphocytes B Magnetic bead purification Magnetism Microspheres Monoclonal antibodies Nanoparticles Purification Recombinant antibodies
Online-Zugang:	Volltext
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