Synthesis and Self-Assembly of the pH-Responsive Anionic Copolymers for Enhanced Doxorubicin-Loading Capacity

Polyelectrolyte complex micelles self-assembled from an ionic polymer and oppositely charged small molecules are a promising drug delivery system. In this study, the anionic block copolymers composed of poly(ethylene glycol), poly(ε-caprolactone), and carboxyl modified poly(ε-caprolactone), COOH-...

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Veröffentlicht in:	Langmuir 2018-07, Vol.34 (26), p.7877-7886
Hauptverfasser:	Yi, Meijun, Lu, Qian, Zhao, Yuping, Cheng, Chenqian, Zhang, Shiping
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Line Cell Survival - drug effects Doxorubicin - administration & dosage Doxorubicin - chemistry Drug Carriers - chemical synthesis Drug Carriers - chemistry Drug Carriers - toxicity Drug Liberation HeLa Cells Humans Hydrogen-Ion Concentration Micelles Particle Size Polymers - chemical synthesis Polymers - chemistry Polymers - toxicity
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