Opinion: The pre-B-cell receptor: selector of fitting immunoglobulin heavy chains for the B-cell repertoire

In this Opinion article, I address the role of the pre-B-cell receptor (pre-BCR) in the development of antigen-specific B cells in terms of immunoglobulin heavy chain (IgH) variable-region repertoire selection, precursor B-cell differentiation and proliferation, and IgH allelic exclusion. Comparison...

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Veröffentlicht in:	Nature reviews. Immunology 2005-07, Vol.5 (7), p.578-584
1. Verfasser:	Melchers, Fritz
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell differentiation Lymphocytes
Online-Zugang:	Volltext
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