Design, synthesis, antimicrobial activity and molecular modeling studies of novel benzofuroxan derivatives against Staphylococcus aureus

A new series of 14 4-substituted [ N′-(benzofuroxan-5-yl)methylene] benzohydrazides with structure analogous of nifuroxazide were synthesized and tested against standard and multidrug-resistant Staphylococcus aureus strains. Molecular modification is a quite promising strategy in the design and deve...

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Veröffentlicht in:Bioorganic & medicinal chemistry 2009-04, Vol.17 (8), p.3028-3036
Hauptverfasser: Jorge, Salomão Dória, Masunari, Andrea, Rangel-Yagui, Carlota Oliveira, Pasqualoto, Kerly Fernanda Mesquita, Tavares, Leoberto Costa
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Sprache:eng
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