Porcine circovirus 2 infection induces IFNβ expression through increased expression of genes involved in RIG-I and IRF7 signaling pathways

•PCV2 infection induces a broad cellular anti-viral response dominated by IFNβ.•The RIG-I/MDA5 viral RNA-sensing pathway was triggered by a DNA viral infection.•The type 1 IFN anti-viral response may paradoxically facilitate PCV2 growth. Porcine circovirus-associated disease (PCVAD), caused by porci...

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Veröffentlicht in:	Virus research 2018-07, Vol.253, p.38-47
Hauptverfasser:	Dvorak, Cheryl M.T., Puvanendiran, Sumathy, Murtaugh, Michael P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Circovirus Differential gene expression Host-Pathogen interaction Immune response Interferon PCV2 Swine Virus
Online-Zugang:	Volltext
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