Capsule-like Safe Genetic VectorsCell-Penetrating Core–Shell Particles Selectively Release Functional Small RNA and Entrap Its Encoding DNA

The breakthrough of genetic therapy is set back by the lack of suitable genetic vector systems. We present the development of permeability-tunable, capsule-like, polymeric, micron-sized, core–shell particles for delivery of recombinant nucleic acids into target cells. These particles were demonstrat...

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Veröffentlicht in:	ACS applied materials & interfaces 2018-06, Vol.10 (25), p.21113-21124
Hauptverfasser:	Yu, Han, Pan, Houwen Matthew, Evalin, Trau, Dieter, Patzel, Volker
Format:	Artikel
Sprache:	eng
Schlagworte:	DNA Genetic Vectors - genetics HEK293 Cells Humans Leukocytes, Mononuclear RNA, Small Interfering
Online-Zugang:	Volltext
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