JZL184, as a monoacylglycerol lipase inhibitor, down-regulates inflammation in a cannabinoid pathway dependent manner

[Display omitted] •Stroke is a prevalent disorder which is associated with several complications including inflammation.•JZL-184 (JZL) inhibits arachidonic acid (AA) production and reduced inflammation.•JZL decreased brain infarction, neurological disorders, TNF-α and MMP9, while, increased IL-10.•J...

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Veröffentlicht in:	Biomedicine & pharmacotherapy 2018-07, Vol.103, p.1720-1726
Hauptverfasser:	Rahmani, Mohammad-Reza, Shamsizadeh, Ali, Moghadam-Ahmadi, Amir, Bazmandegan, Gholamreza, Allahtavakoli, Mohammad
Format:	Artikel
Sprache:	eng
Schlagworte:	AM251 Cannabinoids JZL-184 PMCAO Stroke
Online-Zugang:	Volltext
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