Individualized Mycophenolate Mofetil Dosing Based on Drug Exposure Significantly Improves Patient Outcomes After Renal Transplantation

Efficacy and safety of mycophenolate mofetil (MMF) may be optimized with individualized doses based on therapeutic monitoring of its active metabolite, mycophenolic acid (MPA). In this 12‐month study, 137 renal allograft recipients from 11 French centers receiving basiliximab, cyclosporine A, MMF an...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	American journal of transplantation 2007-11, Vol.7 (11), p.2496-2503
Hauptverfasser:	Le Meur, Y., Büchler, M., Thierry, A., Caillard, S., Villemain, F., Lavaud, S., Etienne, I., Westeel, P.‐F., De Ligny, B. H., Rostaing, L., Thervet, E., Szelag, J. C., Rérolle, J.‐P., Rousseau, A., Touchard, G., Marquet, P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Cortex Hormones - therapeutic use Antibiotics. Antiinfectious agents. Antiparasitic agents Antibodies, Monoclonal - therapeutic use Antiviral agents Area Under Curve Basiliximab Biological and medical sciences Cyclosporine - therapeutic use Dose-Response Relationship, Drug Drug Therapy, Combination Humans Immunosuppressive Agents - administration & dosage Immunosuppressive Agents - therapeutic use Kidney Transplantation - immunology Medical sciences mycophenolate mofetil Mycophenolic Acid - administration & dosage Mycophenolic Acid - analogs & derivatives Mycophenolic Acid - pharmacokinetics Mycophenolic Acid - therapeutic use Pharmacology. Drug treatments Recombinant Fusion Proteins - therapeutic use renal transplantation Safety Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the urinary system therapeutic drug monitoring Transplantation, Homologous
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!