Preparation and protective efficacy of a chicken embryo kidney cell-attenuation GI-19/QX-like avian infectious bronchitis virus vaccine

•A CEK-attenuated QX-like IBV vaccine SczyC100 was prepared.•SczyC100 is effective against prevalent Chinese IBV strains.•The vaccine efficacy of SczyC100 is significantly better than H120. Avian infectious bronchitis (IB) is a highly contagious disease, and hazardous to the poultry industry. Immune...

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Veröffentlicht in:	Vaccine 2018-06, Vol.36 (28), p.4087-4094
Hauptverfasser:	Xia, Jing, He, Xiao, Du, Li-Jing, Liu, Yue-Yue, You, Guo-Jin, Li, Shu-Yun, Liu, Ping, Cao, San-Jie, Han, Xin-Feng, Huang, Yong
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Attenuation Avian infectious bronchitis Bronchitis CEK adaptation Cell Line Chickens China Coronavirus Infections - immunology Coronavirus Infections - pathology Coronavirus Infections - prevention & control Coronavirus Infections - veterinary Design Disease Eggs Embryos Epithelial Cells - virology Infections Infectious bronchitis disease Infectious bronchitis virus - growth & development Infectious bronchitis virus - immunology Infectious bronchitis virus - pathogenicity Influenza Kidneys Laboratory animals Morbidity Mortality Pathogenicity Pathogens Poultry Poultry Diseases - immunology Poultry Diseases - prevention & control Protective Reversion RNA polymerase Safety Serial Passage Serotypes Strains (organisms) Survival Analysis Thermal cycling Trachea Trachea - virology Vaccine Vaccines Vaccines, Attenuated - administration & dosage Vaccines, Attenuated - immunology Vaccines, Attenuated - isolation & purification Veterinary medicine Viral Load Viral Vaccines - administration & dosage Viral Vaccines - immunology Viral Vaccines - isolation & purification Virulence Virus Cultivation - methods Viruses
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