Phage display-derived antibody fragments against conserved regions of VacA toxin of Helicobacter pylori

Infection with Helicobacter pylori may result in the emergence of gastric adenocarcinoma. Among various toxins assisting pathogenesis of H. pylori , the vacuolating cytotoxin A (VacA) is one of the most potent toxins known as the major cause of the peptic ulcer and gastric adenocarcinoma. To isolate...

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Veröffentlicht in:	Applied microbiology and biotechnology 2018-08, Vol.102 (16), p.6899-6913
Hauptverfasser:	Fahimi, Farnaz, Sarhaddi, Shamim, Fouladi, Mehdi, Samadi, Naser, Sadeghi, Javid, Golchin, Asal, Tohidkia, Mohammad Reza, Barar, Jaleh, Omidi, Yadollah
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Affinity Analysis Antibodies Bacteria Bacteriophages Bioinformatics Biomedical and Life Sciences Biotechnological Products and Process Engineering Biotechnology Cancer Colonies Complementarity Diagnostic software Diagnostic systems Display devices Docking Electrophoresis Enzyme-linked immunosorbent assay Flow cytometry Fragments Gel electrophoresis Health risk assessment Helicobacter pylori Immunoblotting Life Sciences Methods Microbial Genetics and Genomics Microbiology Pathogenesis Phage display Phages Plasmids Sodium dodecyl sulfate Sodium lauryl sulfate Structure-function relationships Surface plasmon resonance Toxins Western immunoblotting
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