[alpha]2,6-Sialylation promotes binding of placental protein 14 via its Ca²⁺-dependent lectin activity: insights into differential effects on CD45RO and CD45RA T cells

Placental protein 14 (PP14; glycodelin) is a pregnancy-associated immunoregulatory protein that is known to inhibit T cells via T-cell receptor desensitization. The recent demonstration of PP14 as lectin has provided insight into how it may mediate its CD45 glycoprotein-dependent T-cell inhibition....

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Veröffentlicht in:	Glycobiology (Oxford) 2006-03, Vol.16 (3), p.173-183
Hauptverfasser:	Ish-Shalom, Eliran, Gargir, Ari, André, Sabine, Borovsky, Zipora, Ochanuna, Zohar, Gabius, Hans-Joachim, Tykocinski, Mark L, Rachmilewitz, Jacob
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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