Rapid HPLC Determination of Venlafaxine in Microbial Biotransformation Studies

Venlafaxine is a novel antidepressant, which acts by inhibition of the reuptake of presynaptic noradrenalin and serotonin. In humans, it is metabolized by CYP450 2D6 to an active metabolite O-desmethyl venlafaxine, which has antidepressant activity similar to that of parent drug. Microorganisms have...

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Veröffentlicht in:	Current trends in biotechnology and pharmacy 2009-01, Vol.3 (1), p.64-70
Hauptverfasser:	Vidyavathi, M, Krishna, DR, Prasad, KVSRG, Vidyasagar, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Saccharomyces
Online-Zugang:	Volltext
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