Inhibition of the formation of amyloid β-protein fibrils using biocompatible nanogels as artificial chaperones

The formation of fibrils by amyloid β-protein (Aβ) is considered as a key step in the pathology of Alzheimer’s disease (AD). Inhibiting the aggregation of Aβ is a promising approach for AD therapy. In this study, we used biocompatible nanogels composed of a polysaccharide pullulan backbone with hydr...

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