An integrated analysis of the effects of Esculentin 1–21 on Saccharomyces cerevisiae

The antimicrobial peptide esculentin 1–21 (Esc 1–21) is a shorter synthetic version of the 46-residue peptide occurring in the Rana esculenta skin secretion. Here we propose an integrated proteomic and transcriptomic approach to interpret the biological effects of this peptide on Saccharomyces cerev...

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Veröffentlicht in:	Biochimica et biophysica acta 2007-06, Vol.1774 (6), p.688-700
Hauptverfasser:	Gamberi, Tania, Cavalieri, Duccio, Magherini, Francesca, L. Mangoni, Maria, De Filippo, Carlotta, Borro, Marina, Gentile, Giovanna, Simmaco, Maurizio, Modesti, Alessandra
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - metabolism Amino Acid Sequence Antifungal Agents - chemistry Antifungal Agents - pharmacology Antimicrobial peptide Cell Cycle - drug effects Cytoskeleton - metabolism Electrophoresis, Gel, Two-Dimensional Gene Expression Profiling Gene Expression Regulation, Fungal Genome, Fungal - genetics Glycosides - chemistry Glycosides - pharmacology Heat-Shock Proteins - genetics Microbial Viability - drug effects Molecular Sequence Data Oligonucleotide Array Sequence Analysis Osmotic Pressure - drug effects Peptide Fragments - chemistry Peptide Fragments - pharmacology Pregnenolone - analogs & derivatives Pregnenolone - chemistry Pregnenolone - pharmacology Proteomic Proteomics Rana esculenta S. cerevisiae Saccharomyces cerevisiae Saccharomyces cerevisiae - cytology Saccharomyces cerevisiae - drug effects Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins - genetics Saccharomyces cerevisiae Proteins - metabolism Systems biology Transcription, Genetic - genetics Transcriptomic
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