Important cytotoxic and cytostatic effects of new copper(i)-phosphane compounds with N,N, N,O and N,S bidentate ligands

A family of six phosphane Cu(i) complexes bearing N,N, N,O and N,S bidentate ligands was synthesized. All the compounds were fully characterized by classical analytical and spectroscopic methods, and five of them were also characterized by X-ray diffraction studies. All the compounds exhibit high cy...

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Veröffentlicht in:	Dalton transactions : an international journal of inorganic chemistry 2018, Vol.47 (23), p.7819-7829
Hauptverfasser:	Morais, Tânia S, Jousseaume, Yann, M Piedade, M Fátima, Roma-Rodrigues, Catarina, Fernandes, Alexandra R, Marques, Fernanda, Villa de Brito, Maria J, Garcia, M Helena
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Biocompatibility Breast cancer Cancer Cell cycle Cell death Copper Copper compounds Cytotoxicity In vivo methods and tests Ligands Toxicity X-ray diffraction
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