Role of CD14 in Responses to Clinical Isolates of Escherichia coli: Effects of K1 Capsule Expression

Severe bacterial infections leading to sepsis or septic shock can be induced by bacteria that utilize different factors to drive pathogenicity and/or virulence, leading to disease in the host. One major factor expressed by all clinical isolates of gram-negative bacteria is lipopolysaccharide (LPS);...

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Veröffentlicht in:	Infection and Immunity 2007-11, Vol.75 (11), p.5415-5424
Hauptverfasser:	Metkar, Shalaka, Awasthi, Shanjana, Denamur, Erick, Kim, Kwang Sik, Gangloff, Sophie C, Teichberg, Saul, Haziot, Alain, Silver, Jack, Goyert, Sanna M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Structures - microbiology Animals Antigens, Bacterial - genetics Antigens, Bacterial - immunology Bacterial Capsules - genetics Bacterial Capsules - immunology Bacterial Infections Bacteriology Biological and medical sciences Colony Count, Microbial Disease Susceptibility Escherichia coli Escherichia coli - immunology Escherichia coli - isolation & purification Escherichia coli Infections - microbiology Escherichia coli Infections - mortality Escherichia coli Infections - physiopathology Fundamental and applied biological sciences. Psychology Gene Deletion Immunity, Innate - genetics Interleukin-6 - blood Lipopolysaccharide Receptors - immunology Mice Mice, Inbred BALB C Mice, Knockout Microbiology Miscellaneous Polysaccharides, Bacterial - genetics Polysaccharides, Bacterial - immunology Sepsis - microbiology Survival Analysis Tumor Necrosis Factor-alpha - blood
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