The role of the NLRP3 inflammasome and the activation of IL-1β in the pathogenesis of chronic viral hepatic inflammation

Chronic viral hepatitis is a prevalent disease with major health implications. Its underlying pathophysiological mechanisms are not fully understood. IL-1β and the NLRP3 inflammasome involvement has been suggested in recent years, from in vitro data and data from peripheral blood samples. Therefore,...

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Veröffentlicht in:	Cytokine (Philadelphia, Pa.) Pa.), 2018-10, Vol.110, p.389-396
Hauptverfasser:	Molyvdas, Adam, Georgopoulou, Urania, Lazaridis, Nikolaos, Hytiroglou, Prodromos, Dimitriadis, Alexios, Foka, Pelagia, Vassiliadis, Themistoklis, Loli, Georgia, Phillipidis, Athanasios, Zebekakis, Pantelis, Germenis, Anastasios E., Speletas, Matthaios, Germanidis, Georgios
Format:	Artikel
Sprache:	eng
Schlagworte:	Caspase-1 Chronic HBV HCV Hepatitis IL-1β Inflammation NLRP3
Online-Zugang:	Volltext
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