Modulation by simvastatin of iberiotoxin-sensitive, Ca super(2+)-activated K super(+) channels of porcine coronary artery smooth muscle cells

Background and Purpose: Statins (3-hydroxy-3-methyl-glutaryl coenzyme A (HMG CoA) reductase inhibitors) have been demonstrated to reduce cardiovascular mortality. It is unclear how the expression level of HMG CoA reductase in cardiovascular tissues compares with that in cells derived from the liver....

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Veröffentlicht in:British journal of pharmacology 2007-08, Vol.151 (7), p.987-997
Hauptverfasser: Seto, S W, Au, ALS, Lam, TY, Chim, SSC, Lee, SMY, Wan, S, Tjiu, DCS, Shigemura, N, Yim, APC, Chan, S W, Tsui, SKW, Leung, GPH, Kwan, Y W
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Sprache:eng
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