1H‐MR Spectroscopy Indicates Severity Markers in Temporal Lobe Epilepsy: Correlations between Metabolic Alterations, Seizures, and Epileptic Discharges in EEG

Purpose: In this study, hippocampal metabolite alterations in 1H‐MR spectroscopy (1H‐MRS) were correlated to the findings of intensive video‐EEG monitoring and duration of seizure symptoms in patients with temporal lobe epilepsy (TLE). Methods: The 14 patients with mesial TLE and no pathological fin...

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Veröffentlicht in:	Epilepsia (Copenhagen) 2007-02, Vol.48 (2), p.263-269
Hauptverfasser:	Hammen, Thilo, Schwarz, Michael, Doelken, Marc, Kerling, Frank, Engelhorn, Tobias, Stadlbauer, Andreas, Ganslandt, Oliver, Nimsky, Christopher, Doerfler, Arnd, Stefan, Hermann
Format:	Artikel
Sprache:	eng
Schlagworte:	1H‐MR Spectroscopy Adult Anticonvulsants. Antiepileptics. Antiparkinson agents Aspartic Acid - analogs & derivatives Aspartic Acid - metabolism Biological and medical sciences Biomarkers - metabolism Brain Mapping Choline - metabolism Creatine - metabolism Dipeptides - metabolism Electrodiagnosis. Electric activity recording Electroencephalography - statistics & numerical data Epilepsy, Temporal Lobe - diagnosis Epilepsy, Temporal Lobe - metabolism Epilepsy, Temporal Lobe - physiopathology Epileptic discharges in EEG Female Functional Laterality Glutamine - metabolism Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Hippocampus - metabolism Humans Investigative techniques, diagnostic techniques (general aspects) Magnetic Resonance Spectroscopy - statistics & numerical data Male Medical sciences Metabolic alterations Monitoring, Physiologic Nervous system Nervous system (semeiology, syndromes) Neurology Neuropharmacology Pharmacology. Drug treatments Seizures Seizures - diagnosis Seizures - metabolism Severity of Illness Index Temporal Lobe - metabolism Temporal Lobe - physiopathology Temporal lobe epilepsy Videotape Recording
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