The impact of cytokine gene polymorphisms on the outcome of HLA matched sibling hematopoietic stem cell transplantation

•Cytokines are mediators of immune responses including GVHD.•Polymorphisms of cytokine genes result into high and low producer phenotypes.•There is ethnic variation in high and low producer cytokines genotype/phenotype.•This leads to variation in the contribution to GVHD in different populations. Gr...

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Veröffentlicht in:	Cytokine (Philadelphia, Pa.) Pa.), 2018-10, Vol.110, p.404-411
Hauptverfasser:	Kamel, Azza M., Gameel, Abdallah, Ebid, Gamal T.A., Radwan, Eman R., Mohammed Saleh, Mostafa F., Abdelfattah, Raafat
Format:	Artikel
Sprache:	eng
Schlagworte:	Cytokine gene polymorphism GVHD HSCT IFN-γ IL-10 TGF-β1
Online-Zugang:	Volltext
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