Continuous In‐Line Virus Inactivation for Next Generation Bioprocessing

Viral inactivation plays a critical role in assuring the safety of monoclonal antibody (mAb) therapeutics. Traditional viral inactivation involves large holding tanks in which product is maintained at a target low pH for a defined hold time, typically 30–60 min. The drive toward continuous processin...

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Veröffentlicht in:	Biotechnology journal 2019-02, Vol.14 (2), p.e1700718-n/a
Hauptverfasser:	Gillespie, Christopher, Holstein, Melissa, Mullin, Lori, Cotoni, Kristen, Tuccelli, Ronald, Caulmare, John, Greenhalgh, Patricia
Format:	Artikel
Sprache:	eng
Schlagworte:	continuous inactivation incubation chamber kinetics virus
Online-Zugang:	Volltext
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