Genotoxic Assessment of Different Sizes of Iron Oxide Nanoparticles and Ionic Iron in Earthworm (Eisenia hortensis) Coelomocytes by Comet Assay and Micronucleus Test
The current study was designed to evaluate genotoxicity of different sizes of iron oxide nanoparticles (IONPs) and ionic iron using coelomocytes of the earthworms Eisenia hortensis . Earthworms were exposed to different series of IONPs and ionic iron concentrations to find the respective LC50 of the...
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| Veröffentlicht in: | Bulletin of environmental contamination and toxicology 2018-07, Vol.101 (1), p.105-109 |
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| container_title | Bulletin of environmental contamination and toxicology |
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| creator | Ciğerci, İbrahim Hakkı Ali, Muhammad Muddassir Kaygısız, Şöhret Yüksek Kaya, Bülent Liman, Recep |
| description | The current study was designed to evaluate genotoxicity of different sizes of iron oxide nanoparticles (IONPs) and ionic iron using coelomocytes of the earthworms
Eisenia hortensis
. Earthworms were exposed to different series of IONPs and ionic iron concentrations to find the respective LC50 of the chosen chemicals. LC
50
for |
| doi_str_mv | 10.1007/s00128-018-2364-y |
| format | Article |
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Eisenia hortensis
. Earthworms were exposed to different series of IONPs and ionic iron concentrations to find the respective LC50 of the chosen chemicals. LC
50
for < 50, <100 nm and the ionic iron of IONPs were 500, 200, 250 µg/mL respectively. Concentrations of LC
50
/2 (250, 100, 125 µg/mL for < 50, <100 nm and the ionic iron respectively) and LC
50
for 48 h were used to perform the comet assay and micronucleus test. Statistically significant (
p
< 0.05) increase in DNA and chromosomal damage was observed for all sizes of IONPs and ionic iron. In the comet assay system, the greatest genotoxicity was observed in the treatments with < 100 nm IONPs, whereas the greatest numbers of micronuclei and binucleate cells were observed in the treatments with ionic iron. It was concluded that different types of nanoparticles (i.e. sizes, shapes) may have different genotoxic potencies in different assays with
E. hortensis
earthworms.]]></description><identifier>ISSN: 0007-4861</identifier><identifier>EISSN: 1432-0800</identifier><identifier>DOI: 10.1007/s00128-018-2364-y</identifier><identifier>PMID: 29802429</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Aquatic Pollution ; Bioassays ; Chromosome aberrations ; Coelomocytes ; Comet assay ; Damage detection ; Deoxyribonucleic acid ; DNA ; DNA damage ; Earth and Environmental Science ; Ecotoxicology ; Eisenia hortensis ; Environment ; Environmental Chemistry ; Environmental Health ; Genotoxicity ; Iron oxides ; Micronuclei ; Nanoparticles ; Oligochaeta ; Pollution ; Soil Science & Conservation ; Statistical analysis ; Waste Water Technology ; Water Management ; Water Pollution Control</subject><ispartof>Bulletin of environmental contamination and toxicology, 2018-07, Vol.101 (1), p.105-109</ispartof><rights>Springer Science+Business Media, LLC, part of Springer Nature 2018</rights><rights>Bulletin of Environmental Contamination and Toxicology is a copyright of Springer, (2018). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c372t-cdcb9e4e77cd48fa665157926d87d0cfe476b94ff937864d3b6ba14aee8021bf3</citedby><cites>FETCH-LOGICAL-c372t-cdcb9e4e77cd48fa665157926d87d0cfe476b94ff937864d3b6ba14aee8021bf3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00128-018-2364-y$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00128-018-2364-y$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29802429$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ciğerci, İbrahim Hakkı</creatorcontrib><creatorcontrib>Ali, Muhammad Muddassir</creatorcontrib><creatorcontrib>Kaygısız, Şöhret Yüksek</creatorcontrib><creatorcontrib>Kaya, Bülent</creatorcontrib><creatorcontrib>Liman, Recep</creatorcontrib><title>Genotoxic Assessment of Different Sizes of Iron Oxide Nanoparticles and Ionic Iron in Earthworm (Eisenia hortensis) Coelomocytes by Comet Assay and Micronucleus Test</title><title>Bulletin of environmental contamination and toxicology</title><addtitle>Bull Environ Contam Toxicol</addtitle><addtitle>Bull Environ Contam Toxicol</addtitle><description><![CDATA[The current study was designed to evaluate genotoxicity of different sizes of iron oxide nanoparticles (IONPs) and ionic iron using coelomocytes of the earthworms
Eisenia hortensis
. Earthworms were exposed to different series of IONPs and ionic iron concentrations to find the respective LC50 of the chosen chemicals. LC
50
for < 50, <100 nm and the ionic iron of IONPs were 500, 200, 250 µg/mL respectively. Concentrations of LC
50
/2 (250, 100, 125 µg/mL for < 50, <100 nm and the ionic iron respectively) and LC
50
for 48 h were used to perform the comet assay and micronucleus test. Statistically significant (
p
< 0.05) increase in DNA and chromosomal damage was observed for all sizes of IONPs and ionic iron. In the comet assay system, the greatest genotoxicity was observed in the treatments with < 100 nm IONPs, whereas the greatest numbers of micronuclei and binucleate cells were observed in the treatments with ionic iron. It was concluded that different types of nanoparticles (i.e. sizes, shapes) may have different genotoxic potencies in different assays with
E. hortensis
earthworms.]]></description><subject>Aquatic Pollution</subject><subject>Bioassays</subject><subject>Chromosome aberrations</subject><subject>Coelomocytes</subject><subject>Comet assay</subject><subject>Damage detection</subject><subject>Deoxyribonucleic acid</subject><subject>DNA</subject><subject>DNA damage</subject><subject>Earth and Environmental Science</subject><subject>Ecotoxicology</subject><subject>Eisenia hortensis</subject><subject>Environment</subject><subject>Environmental Chemistry</subject><subject>Environmental Health</subject><subject>Genotoxicity</subject><subject>Iron oxides</subject><subject>Micronuclei</subject><subject>Nanoparticles</subject><subject>Oligochaeta</subject><subject>Pollution</subject><subject>Soil Science & Conservation</subject><subject>Statistical analysis</subject><subject>Waste Water Technology</subject><subject>Water Management</subject><subject>Water Pollution Control</subject><issn>0007-4861</issn><issn>1432-0800</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp1kc9u1DAQxi0EotvCA3BBlri0h4DtePPnWC1LWanQA-UcOc6YukrsxZOoDe_DezLpFpCQOFnj-c332fMx9kqKt1KI8h0KIVWVCVllKi90Nj9hK6lzlYlKiKdsJQjKdFXII3aMeEv0ulLqOTtSdSWUVvWK_byAEMd47y0_RwTEAcLIo-PvvXOQluKL_wG4XO1SDPzq3nfAP5sQ9yaN3vbUM6HjuxhI4wHxgW-pd3MX08BPtx4heMNvYhohoMczvonQxyHaeaThdqZ6gHHxN_OD1idvSWci7Qn5NeD4gj1zpkd4-XiesK8fttebj9nl1cVuc36Z2bxUY2Y729agoSxtpytnimIt12Wtiq4qO2Ed6LJoa-1cnZdVobu8LVojtQGgdcjW5Sfs9KC7T_H7RMbN4NFC35sAccJGCb1WRU1LJPTNP-htnFKg1y2Ups2vZUmUPFD0IcQErtknP5g0N1I0S4bNIcOGMmyWDJuZZl4_Kk_tAN2fid-hEaAOAFIrfIP01_r_qr8AeVSp2g</recordid><startdate>20180701</startdate><enddate>20180701</enddate><creator>Ciğerci, İbrahim Hakkı</creator><creator>Ali, Muhammad Muddassir</creator><creator>Kaygısız, Şöhret Yüksek</creator><creator>Kaya, Bülent</creator><creator>Liman, Recep</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7T7</scope><scope>7TK</scope><scope>7TV</scope><scope>7U7</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8C1</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>P64</scope><scope>PATMY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PYCSY</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20180701</creationdate><title>Genotoxic Assessment of Different Sizes of Iron Oxide Nanoparticles and Ionic Iron in Earthworm (Eisenia hortensis) Coelomocytes by Comet Assay and Micronucleus Test</title><author>Ciğerci, İbrahim Hakkı ; Ali, Muhammad Muddassir ; Kaygısız, Şöhret Yüksek ; Kaya, Bülent ; Liman, Recep</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c372t-cdcb9e4e77cd48fa665157926d87d0cfe476b94ff937864d3b6ba14aee8021bf3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Aquatic Pollution</topic><topic>Bioassays</topic><topic>Chromosome aberrations</topic><topic>Coelomocytes</topic><topic>Comet assay</topic><topic>Damage detection</topic><topic>Deoxyribonucleic acid</topic><topic>DNA</topic><topic>DNA damage</topic><topic>Earth and Environmental Science</topic><topic>Ecotoxicology</topic><topic>Eisenia hortensis</topic><topic>Environment</topic><topic>Environmental Chemistry</topic><topic>Environmental Health</topic><topic>Genotoxicity</topic><topic>Iron oxides</topic><topic>Micronuclei</topic><topic>Nanoparticles</topic><topic>Oligochaeta</topic><topic>Pollution</topic><topic>Soil Science & Conservation</topic><topic>Statistical analysis</topic><topic>Waste Water Technology</topic><topic>Water Management</topic><topic>Water Pollution Control</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ciğerci, İbrahim Hakkı</creatorcontrib><creatorcontrib>Ali, Muhammad Muddassir</creatorcontrib><creatorcontrib>Kaygısız, Şöhret Yüksek</creatorcontrib><creatorcontrib>Kaya, Bülent</creatorcontrib><creatorcontrib>Liman, Recep</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Neurosciences Abstracts</collection><collection>Pollution Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>Environmental Science Collection</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Bulletin of environmental contamination and toxicology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ciğerci, İbrahim Hakkı</au><au>Ali, Muhammad Muddassir</au><au>Kaygısız, Şöhret Yüksek</au><au>Kaya, Bülent</au><au>Liman, Recep</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Genotoxic Assessment of Different Sizes of Iron Oxide Nanoparticles and Ionic Iron in Earthworm (Eisenia hortensis) Coelomocytes by Comet Assay and Micronucleus Test</atitle><jtitle>Bulletin of environmental contamination and toxicology</jtitle><stitle>Bull Environ Contam Toxicol</stitle><addtitle>Bull Environ Contam Toxicol</addtitle><date>2018-07-01</date><risdate>2018</risdate><volume>101</volume><issue>1</issue><spage>105</spage><epage>109</epage><pages>105-109</pages><issn>0007-4861</issn><eissn>1432-0800</eissn><abstract><![CDATA[The current study was designed to evaluate genotoxicity of different sizes of iron oxide nanoparticles (IONPs) and ionic iron using coelomocytes of the earthworms
Eisenia hortensis
. Earthworms were exposed to different series of IONPs and ionic iron concentrations to find the respective LC50 of the chosen chemicals. LC
50
for < 50, <100 nm and the ionic iron of IONPs were 500, 200, 250 µg/mL respectively. Concentrations of LC
50
/2 (250, 100, 125 µg/mL for < 50, <100 nm and the ionic iron respectively) and LC
50
for 48 h were used to perform the comet assay and micronucleus test. Statistically significant (
p
< 0.05) increase in DNA and chromosomal damage was observed for all sizes of IONPs and ionic iron. In the comet assay system, the greatest genotoxicity was observed in the treatments with < 100 nm IONPs, whereas the greatest numbers of micronuclei and binucleate cells were observed in the treatments with ionic iron. It was concluded that different types of nanoparticles (i.e. sizes, shapes) may have different genotoxic potencies in different assays with
E. hortensis
earthworms.]]></abstract><cop>New York</cop><pub>Springer US</pub><pmid>29802429</pmid><doi>10.1007/s00128-018-2364-y</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0007-4861 |
| ispartof | Bulletin of environmental contamination and toxicology, 2018-07, Vol.101 (1), p.105-109 |
| issn | 0007-4861 1432-0800 |
| language | eng |
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| source | SpringerLink Journals - AutoHoldings |
| subjects | Aquatic Pollution Bioassays Chromosome aberrations Coelomocytes Comet assay Damage detection Deoxyribonucleic acid DNA DNA damage Earth and Environmental Science Ecotoxicology Eisenia hortensis Environment Environmental Chemistry Environmental Health Genotoxicity Iron oxides Micronuclei Nanoparticles Oligochaeta Pollution Soil Science & Conservation Statistical analysis Waste Water Technology Water Management Water Pollution Control |
| title | Genotoxic Assessment of Different Sizes of Iron Oxide Nanoparticles and Ionic Iron in Earthworm (Eisenia hortensis) Coelomocytes by Comet Assay and Micronucleus Test |
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