Increased immune cell infiltration in patient-derived tumor explants treated with Traniplatin: an original Pt(iv) pro-drug based on Cisplatin and Tranilast

Elevated intra-tumoral immune infiltrate is associated with an improved prognosis in cancer of distinct origins. Traniplatin (TPT) is a novel platinum(iv) pro-drug based on Cisplatin (CDDP) and the marketed drug Tranilast. When compared in vitro to Cisplatin, TPT showed increased cytotoxic activity...

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Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2018, Vol.54 (60), p.8324-8327
Hauptverfasser:	Lo Re, Daniele, Montagner, Diego, Tolan, Dina, Di Sanza, Claudio, Iglesias, Mar, Calon, Alexandre, Giralt, E
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Colon Colorectal cancer Cytotoxicity Immune system Infiltration Platinum Tumors
Online-Zugang:	Volltext
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