Carcinogen exposure differentially modulates RAR-[beta] promoter hypermethylation, an early and frequent event in mouse lung carcinogenesis

The retinoic acid receptor beta (RAR-[beta]) gene encodes one of the primary receptors for retinoic acid, an important signaling molecule in lung growth, differentiation and carcinogenesis. RAR-[beta] has been shown to be down-regulated by methylation in human lung cancer. We have used previously lu...

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Veröffentlicht in:	Carcinogenesis (New York) 2004-04, Vol.25 (4), p.623-623
Hauptverfasser:	Vuillemenot, Brian R, Pulling, Leah C, Palmisano, William A, Hutt, Julie A, Belinsky, Steven A
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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