Loss of hippocampal neuronal nitric oxide synthase contributes to the stress-related deficit in learning and memory

Nitric oxide (NO) has been involved in many pathophysiological brain processes. However, the exact role of NO in the cognitive deficit associated to chronic stress exposure has not been elucidated. In this study, we investigated the participation of hippocampal NO production and their regulation by...

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Veröffentlicht in:	Journal of neurochemistry 2007-07, Vol.102 (1), p.261-274
Hauptverfasser:	Palumbo, María Laura, Fosser, Nicolás Sebastián, Rios, Hugo, Zubilete, María Aurelia Zorrilla, Guelman, Laura Ruth, Cremaschi, Graciela Alicia, Genaro, Ana María
Format:	Artikel
Sprache:	eng
Schlagworte:	Ageing, cell death Animals Avoidance Learning - physiology Biochemistry Biological and medical sciences Blotting, Western Brain Cell physiology Chronic Disease chronic mild stress Enzymes Female Fundamental and applied biological sciences. Psychology General pharmacology hippocampus Hippocampus - enzymology Immunohistochemistry Isoenzymes - metabolism Kinases learning Learning Disorders - enzymology Learning Disorders - etiology Learning Disorders - psychology Medical sciences Memory Memory Disorders - enzymology Memory Disorders - etiology Memory Disorders - psychology Mice Mice, Inbred BALB C Molecular and cellular biology N-Methylaspartate - pharmacology Neurology Neuronal Plasticity - physiology Nitric oxide Nitric Oxide - biosynthesis Nitric Oxide - physiology nitric oxide synthase Nitric Oxide Synthase Type I - metabolism Nitric Oxide Synthase Type I - physiology Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments protein kinase C Protein Kinase C - metabolism Protein Kinase C-alpha - metabolism Protein Kinase C-epsilon - metabolism Reactive Oxygen Species - metabolism recactive oxygen species Signal Transduction - physiology Stress Stress, Psychological - complications Stress, Psychological - enzymology Stress, Psychological - psychology
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