Risk-adapted treatment of acute promyelocytic leukemia: results from the International Consortium for Childhood APL

Pediatric acute promyelocytic leukemia (APL) can be cured with all-trans retinoic acid (ATRA) and anthracycline. However, most published trials have employed high cumulative doses of anthracyclines. Here, we report the outcome of newly diagnosed APL patients enrolled in the International Consortium...

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Veröffentlicht in:	Blood 2018-07, Vol.132 (4), p.405-412
Hauptverfasser:	Testi, Anna Maria, Pession, Andrea, Diverio, Daniela, Grimwade, David, Gibson, Brenda, de Azevedo, Amilcar Cardoso, Moran, Lorena, Leverger, Guy, Elitzur, Sarah, Hasle, Henrik, ten Bosch, Jutte van der Werff, Smith, Owen, De Rosa, Marisa, Piciocchi, Alfonso, Lo Coco, Francesco, Foà, Robin, Locatelli, Franco, Kaspers, Gertjan J.L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Anthracyclines - administration & dosage Antineoplastic Combined Chemotherapy Protocols - therapeutic use Child Child, Preschool Daunorubicin - administration & dosage Female Humans Idarubicin - administration & dosage Infant International Agencies Leukemia, Promyelocytic, Acute - drug therapy Leukemia, Promyelocytic, Acute - pathology Male Remission Induction Risk Factors Treatment Outcome Tretinoin - administration & dosage Young Adult
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