Cytokine IL9 Triggers the Pathogenesis of Inflammatory Bowel Disease Through the miR21-CLDN8 Pathway

Abstract Background Cytokine interleukin-9 (IL9) plays an essential role in the pathogenesis of inflammatory bowel disease. However, the molecular mechanism underlying the IL9 pathway remains unknown. Here, we initiate a series of studies to characterize the essential components of this pathway. Met...

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Veröffentlicht in:	Inflammatory bowel diseases 2018-09, Vol.24 (10), p.2211-2223
Hauptverfasser:	Li, Li, Huang, Shanshan, Wang, Huiling, Chao, Kang, Ding, Li, Feng, Rui, Qiu, Yun, Feng, Ting, Zhou, Gaoshi, Hu, Ji-Fan, Chen, Minhu, Zhang, Shenghong
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Caco-2 Cells Case-Control Studies Claudins - genetics Claudins - metabolism Colitis - chemically induced Colitis - genetics Colitis - metabolism Colitis - pathology Crohn Disease - genetics Crohn Disease - metabolism Crohn Disease - pathology Follow-Up Studies Humans Interleukin-9 - genetics Interleukin-9 - metabolism Male Mice Mice, Inbred BALB C MicroRNAs - genetics Trinitrobenzenesulfonic Acid - toxicity
Online-Zugang:	Volltext
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