Meniscal pathologies on MRI correlate with increased bone tracer uptake in SPECT/CT
Objectives To assess the relationship of subchondral bone tracer uptake (BTU) on SPECT/CT and meniscal pathologies on MRI in patients with painful knees. Methods Twenty-five patients who had MRI and SPECT/CT within 3 months without knee surgery or grade ≥3 cartilage lesions were prospectively includ...
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| Veröffentlicht in: | European radiology 2018-11, Vol.28 (11), p.4696-4704 |
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| creator | Rechsteiner, Jan Hirschmann, Michael T. Dordevic, Milos Falkowski, Anna L. Testa, Enrique A. Amsler, Felix Hirschmann, Anna |
| description | Objectives
To assess the relationship of subchondral bone tracer uptake (BTU) on SPECT/CT and meniscal pathologies on MRI in patients with painful knees.
Methods
Twenty-five patients who had MRI and SPECT/CT within 3 months without knee surgery or grade ≥3 cartilage lesions were prospectively included. Maximum values of each subchondral femorotibial area were quantified and a ratio was calculated in relation to a femoral shaft reference region, which represented the BTU background activity. Meniscal lesions were graded (intact/degeneration/tear) and meniscal extrusion (no/yes) was assessed using MRI by two musculoskeletal radiologists blinded to the SPECT/CT findings. One-tailed Spearman correlations served for statistics (
p
< 0.05).
Results
Knees with meniscal degeneration or tear showed a significantly higher BTU in the medial femorotibial compartment (
p
= 0.045) when compared to intact menisci. Meniscal degeneration was associated with an increased BTU in the lateral femorotibial compartment; however, this was not statistically significant (
p
= 0.143). Patients with an extruded meniscus showed significantly higher BTU compared to a non-extruded meniscus (
p
< 0.020).
Conclusions
Medial femorotibial BTU in SPECT/CT was associated with meniscal pathologies. Highest BTU was found in patients with meniscal tears. SPECT/CT appears to be a useful imaging modality to identify patients with overloading or early osteoarthritis.
Key Points
•
Meniscal degeneration and tears correlate significantly with increased BTU using SPECT/CT.
•
Medial meniscus extrusion is associated with an increased BTU in SPECT/CT.
•
SPECT/CT allows detection of overloading and early osteoarthritis. |
| doi_str_mv | 10.1007/s00330-018-5466-3 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2043168406</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2042475838</sourcerecordid><originalsourceid>FETCH-LOGICAL-c398t-79d062157fcd001bf15918084a33dd4eb54d19ee6006afdba876831e695d96853</originalsourceid><addsrcrecordid>eNp1kMtKxDAUhoMoOl4ewI0E3LipnjRpmixl8AaKouM6pM2pVjvNmLSIb2-G8QKCqyzOd_785yNkn8ExAyhPIgDnkAFTWSGkzPgamTDB84yBEutkApqrrNRabJHtGF8AQDNRbpKtXJdKa5ZPyMMN9m2sbUcXdnj2nX9qMVLf05v7K1r7ELCzA9L3dnimbV8HtBEdrXyPdAi2xkDHxWBfMQ3pw93ZdHYyne2SjcZ2Efe-3h3yeH42m15m17cXV9PT66zmWg2pmAOZs6JsagfAqoYVmqnU3HLunMCqEI5pRAkgbeMqq0qpOEOpC6elKvgOOVrlLoJ_GzEOZp5Owa6zPfoxmhwEZ1IJkAk9_IO--DH0qd2SykVZKK4SxVZUHXyMARuzCO3chg_DwCyNm5Vxk4ybpXHD087BV_JYzdH9bHwrTkC-AmIa9U8Yfr_-P_UTmKuJFg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2042475838</pqid></control><display><type>article</type><title>Meniscal pathologies on MRI correlate with increased bone tracer uptake in SPECT/CT</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>Rechsteiner, Jan ; Hirschmann, Michael T. ; Dordevic, Milos ; Falkowski, Anna L. ; Testa, Enrique A. ; Amsler, Felix ; Hirschmann, Anna</creator><creatorcontrib>Rechsteiner, Jan ; Hirschmann, Michael T. ; Dordevic, Milos ; Falkowski, Anna L. ; Testa, Enrique A. ; Amsler, Felix ; Hirschmann, Anna</creatorcontrib><description>Objectives
To assess the relationship of subchondral bone tracer uptake (BTU) on SPECT/CT and meniscal pathologies on MRI in patients with painful knees.
Methods
Twenty-five patients who had MRI and SPECT/CT within 3 months without knee surgery or grade ≥3 cartilage lesions were prospectively included. Maximum values of each subchondral femorotibial area were quantified and a ratio was calculated in relation to a femoral shaft reference region, which represented the BTU background activity. Meniscal lesions were graded (intact/degeneration/tear) and meniscal extrusion (no/yes) was assessed using MRI by two musculoskeletal radiologists blinded to the SPECT/CT findings. One-tailed Spearman correlations served for statistics (
p
< 0.05).
Results
Knees with meniscal degeneration or tear showed a significantly higher BTU in the medial femorotibial compartment (
p
= 0.045) when compared to intact menisci. Meniscal degeneration was associated with an increased BTU in the lateral femorotibial compartment; however, this was not statistically significant (
p
= 0.143). Patients with an extruded meniscus showed significantly higher BTU compared to a non-extruded meniscus (
p
< 0.020).
Conclusions
Medial femorotibial BTU in SPECT/CT was associated with meniscal pathologies. Highest BTU was found in patients with meniscal tears. SPECT/CT appears to be a useful imaging modality to identify patients with overloading or early osteoarthritis.
Key Points
•
Meniscal degeneration and tears correlate significantly with increased BTU using SPECT/CT.
•
Medial meniscus extrusion is associated with an increased BTU in SPECT/CT.
•
SPECT/CT allows detection of overloading and early osteoarthritis.</description><identifier>ISSN: 0938-7994</identifier><identifier>EISSN: 1432-1084</identifier><identifier>DOI: 10.1007/s00330-018-5466-3</identifier><identifier>PMID: 29789912</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Adult ; Aged ; Arthralgia - diagnosis ; Arthralgia - etiology ; Arthralgia - metabolism ; Arthritis ; Biocompatibility ; Biomedical materials ; Cartilage ; Cartilage diseases ; Computed tomography ; Correlation ; Degeneration ; Diagnostic Radiology ; Extrusion ; Female ; Femur ; Follow-Up Studies ; Humans ; Imaging ; Injuries ; Internal Medicine ; Interventional Radiology ; Knee ; Knee Joint - diagnostic imaging ; Knee Joint - metabolism ; Lesions ; Magnetic resonance imaging ; Magnetic Resonance Imaging - methods ; Male ; Medicine ; Medicine & Public Health ; Menisci, Tibial - diagnostic imaging ; Menisci, Tibial - metabolism ; Meniscus ; Middle Aged ; Musculoskeletal ; Neuroradiology ; Osteoarthritis ; Osteoarthritis, Knee - complications ; Osteoarthritis, Knee - diagnosis ; Osteoarthritis, Knee - metabolism ; Overloading ; Patients ; Positron Emission Tomography Computed Tomography - methods ; Prospective Studies ; Radiology ; Radiopharmaceuticals - pharmacokinetics ; ROC Curve ; Single photon emission computed tomography ; Statistical analysis ; Subchondral bone ; Surgery ; Tearing ; Technetium Tc 99m Medronate - analogs & derivatives ; Technetium Tc 99m Medronate - pharmacokinetics ; Ultrasound ; Young Adult</subject><ispartof>European radiology, 2018-11, Vol.28 (11), p.4696-4704</ispartof><rights>European Society of Radiology 2018</rights><rights>European Radiology is a copyright of Springer, (2018). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c398t-79d062157fcd001bf15918084a33dd4eb54d19ee6006afdba876831e695d96853</citedby><cites>FETCH-LOGICAL-c398t-79d062157fcd001bf15918084a33dd4eb54d19ee6006afdba876831e695d96853</cites><orcidid>0000-0003-1560-0247</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00330-018-5466-3$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00330-018-5466-3$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29789912$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rechsteiner, Jan</creatorcontrib><creatorcontrib>Hirschmann, Michael T.</creatorcontrib><creatorcontrib>Dordevic, Milos</creatorcontrib><creatorcontrib>Falkowski, Anna L.</creatorcontrib><creatorcontrib>Testa, Enrique A.</creatorcontrib><creatorcontrib>Amsler, Felix</creatorcontrib><creatorcontrib>Hirschmann, Anna</creatorcontrib><title>Meniscal pathologies on MRI correlate with increased bone tracer uptake in SPECT/CT</title><title>European radiology</title><addtitle>Eur Radiol</addtitle><addtitle>Eur Radiol</addtitle><description>Objectives
To assess the relationship of subchondral bone tracer uptake (BTU) on SPECT/CT and meniscal pathologies on MRI in patients with painful knees.
Methods
Twenty-five patients who had MRI and SPECT/CT within 3 months without knee surgery or grade ≥3 cartilage lesions were prospectively included. Maximum values of each subchondral femorotibial area were quantified and a ratio was calculated in relation to a femoral shaft reference region, which represented the BTU background activity. Meniscal lesions were graded (intact/degeneration/tear) and meniscal extrusion (no/yes) was assessed using MRI by two musculoskeletal radiologists blinded to the SPECT/CT findings. One-tailed Spearman correlations served for statistics (
p
< 0.05).
Results
Knees with meniscal degeneration or tear showed a significantly higher BTU in the medial femorotibial compartment (
p
= 0.045) when compared to intact menisci. Meniscal degeneration was associated with an increased BTU in the lateral femorotibial compartment; however, this was not statistically significant (
p
= 0.143). Patients with an extruded meniscus showed significantly higher BTU compared to a non-extruded meniscus (
p
< 0.020).
Conclusions
Medial femorotibial BTU in SPECT/CT was associated with meniscal pathologies. Highest BTU was found in patients with meniscal tears. SPECT/CT appears to be a useful imaging modality to identify patients with overloading or early osteoarthritis.
Key Points
•
Meniscal degeneration and tears correlate significantly with increased BTU using SPECT/CT.
•
Medial meniscus extrusion is associated with an increased BTU in SPECT/CT.
•
SPECT/CT allows detection of overloading and early osteoarthritis.</description><subject>Adult</subject><subject>Aged</subject><subject>Arthralgia - diagnosis</subject><subject>Arthralgia - etiology</subject><subject>Arthralgia - metabolism</subject><subject>Arthritis</subject><subject>Biocompatibility</subject><subject>Biomedical materials</subject><subject>Cartilage</subject><subject>Cartilage diseases</subject><subject>Computed tomography</subject><subject>Correlation</subject><subject>Degeneration</subject><subject>Diagnostic Radiology</subject><subject>Extrusion</subject><subject>Female</subject><subject>Femur</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Imaging</subject><subject>Injuries</subject><subject>Internal Medicine</subject><subject>Interventional Radiology</subject><subject>Knee</subject><subject>Knee Joint - diagnostic imaging</subject><subject>Knee Joint - metabolism</subject><subject>Lesions</subject><subject>Magnetic resonance imaging</subject><subject>Magnetic Resonance Imaging - methods</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Menisci, Tibial - diagnostic imaging</subject><subject>Menisci, Tibial - metabolism</subject><subject>Meniscus</subject><subject>Middle Aged</subject><subject>Musculoskeletal</subject><subject>Neuroradiology</subject><subject>Osteoarthritis</subject><subject>Osteoarthritis, Knee - complications</subject><subject>Osteoarthritis, Knee - diagnosis</subject><subject>Osteoarthritis, Knee - metabolism</subject><subject>Overloading</subject><subject>Patients</subject><subject>Positron Emission Tomography Computed Tomography - methods</subject><subject>Prospective Studies</subject><subject>Radiology</subject><subject>Radiopharmaceuticals - pharmacokinetics</subject><subject>ROC Curve</subject><subject>Single photon emission computed tomography</subject><subject>Statistical analysis</subject><subject>Subchondral bone</subject><subject>Surgery</subject><subject>Tearing</subject><subject>Technetium Tc 99m Medronate - analogs & derivatives</subject><subject>Technetium Tc 99m Medronate - pharmacokinetics</subject><subject>Ultrasound</subject><subject>Young Adult</subject><issn>0938-7994</issn><issn>1432-1084</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp1kMtKxDAUhoMoOl4ewI0E3LipnjRpmixl8AaKouM6pM2pVjvNmLSIb2-G8QKCqyzOd_785yNkn8ExAyhPIgDnkAFTWSGkzPgamTDB84yBEutkApqrrNRabJHtGF8AQDNRbpKtXJdKa5ZPyMMN9m2sbUcXdnj2nX9qMVLf05v7K1r7ELCzA9L3dnimbV8HtBEdrXyPdAi2xkDHxWBfMQ3pw93ZdHYyne2SjcZ2Efe-3h3yeH42m15m17cXV9PT66zmWg2pmAOZs6JsagfAqoYVmqnU3HLunMCqEI5pRAkgbeMqq0qpOEOpC6elKvgOOVrlLoJ_GzEOZp5Owa6zPfoxmhwEZ1IJkAk9_IO--DH0qd2SykVZKK4SxVZUHXyMARuzCO3chg_DwCyNm5Vxk4ybpXHD087BV_JYzdH9bHwrTkC-AmIa9U8Yfr_-P_UTmKuJFg</recordid><startdate>20181101</startdate><enddate>20181101</enddate><creator>Rechsteiner, Jan</creator><creator>Hirschmann, Michael T.</creator><creator>Dordevic, Milos</creator><creator>Falkowski, Anna L.</creator><creator>Testa, Enrique A.</creator><creator>Amsler, Felix</creator><creator>Hirschmann, Anna</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-1560-0247</orcidid></search><sort><creationdate>20181101</creationdate><title>Meniscal pathologies on MRI correlate with increased bone tracer uptake in SPECT/CT</title><author>Rechsteiner, Jan ; Hirschmann, Michael T. ; Dordevic, Milos ; Falkowski, Anna L. ; Testa, Enrique A. ; Amsler, Felix ; Hirschmann, Anna</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c398t-79d062157fcd001bf15918084a33dd4eb54d19ee6006afdba876831e695d96853</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Arthralgia - diagnosis</topic><topic>Arthralgia - etiology</topic><topic>Arthralgia - metabolism</topic><topic>Arthritis</topic><topic>Biocompatibility</topic><topic>Biomedical materials</topic><topic>Cartilage</topic><topic>Cartilage diseases</topic><topic>Computed tomography</topic><topic>Correlation</topic><topic>Degeneration</topic><topic>Diagnostic Radiology</topic><topic>Extrusion</topic><topic>Female</topic><topic>Femur</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Imaging</topic><topic>Injuries</topic><topic>Internal Medicine</topic><topic>Interventional Radiology</topic><topic>Knee</topic><topic>Knee Joint - diagnostic imaging</topic><topic>Knee Joint - metabolism</topic><topic>Lesions</topic><topic>Magnetic resonance imaging</topic><topic>Magnetic Resonance Imaging - methods</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Menisci, Tibial - diagnostic imaging</topic><topic>Menisci, Tibial - metabolism</topic><topic>Meniscus</topic><topic>Middle Aged</topic><topic>Musculoskeletal</topic><topic>Neuroradiology</topic><topic>Osteoarthritis</topic><topic>Osteoarthritis, Knee - complications</topic><topic>Osteoarthritis, Knee - diagnosis</topic><topic>Osteoarthritis, Knee - metabolism</topic><topic>Overloading</topic><topic>Patients</topic><topic>Positron Emission Tomography Computed Tomography - methods</topic><topic>Prospective Studies</topic><topic>Radiology</topic><topic>Radiopharmaceuticals - pharmacokinetics</topic><topic>ROC Curve</topic><topic>Single photon emission computed tomography</topic><topic>Statistical analysis</topic><topic>Subchondral bone</topic><topic>Surgery</topic><topic>Tearing</topic><topic>Technetium Tc 99m Medronate - analogs & derivatives</topic><topic>Technetium Tc 99m Medronate - pharmacokinetics</topic><topic>Ultrasound</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rechsteiner, Jan</creatorcontrib><creatorcontrib>Hirschmann, Michael T.</creatorcontrib><creatorcontrib>Dordevic, Milos</creatorcontrib><creatorcontrib>Falkowski, Anna L.</creatorcontrib><creatorcontrib>Testa, Enrique A.</creatorcontrib><creatorcontrib>Amsler, Felix</creatorcontrib><creatorcontrib>Hirschmann, Anna</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>European radiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rechsteiner, Jan</au><au>Hirschmann, Michael T.</au><au>Dordevic, Milos</au><au>Falkowski, Anna L.</au><au>Testa, Enrique A.</au><au>Amsler, Felix</au><au>Hirschmann, Anna</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Meniscal pathologies on MRI correlate with increased bone tracer uptake in SPECT/CT</atitle><jtitle>European radiology</jtitle><stitle>Eur Radiol</stitle><addtitle>Eur Radiol</addtitle><date>2018-11-01</date><risdate>2018</risdate><volume>28</volume><issue>11</issue><spage>4696</spage><epage>4704</epage><pages>4696-4704</pages><issn>0938-7994</issn><eissn>1432-1084</eissn><abstract>Objectives
To assess the relationship of subchondral bone tracer uptake (BTU) on SPECT/CT and meniscal pathologies on MRI in patients with painful knees.
Methods
Twenty-five patients who had MRI and SPECT/CT within 3 months without knee surgery or grade ≥3 cartilage lesions were prospectively included. Maximum values of each subchondral femorotibial area were quantified and a ratio was calculated in relation to a femoral shaft reference region, which represented the BTU background activity. Meniscal lesions were graded (intact/degeneration/tear) and meniscal extrusion (no/yes) was assessed using MRI by two musculoskeletal radiologists blinded to the SPECT/CT findings. One-tailed Spearman correlations served for statistics (
p
< 0.05).
Results
Knees with meniscal degeneration or tear showed a significantly higher BTU in the medial femorotibial compartment (
p
= 0.045) when compared to intact menisci. Meniscal degeneration was associated with an increased BTU in the lateral femorotibial compartment; however, this was not statistically significant (
p
= 0.143). Patients with an extruded meniscus showed significantly higher BTU compared to a non-extruded meniscus (
p
< 0.020).
Conclusions
Medial femorotibial BTU in SPECT/CT was associated with meniscal pathologies. Highest BTU was found in patients with meniscal tears. SPECT/CT appears to be a useful imaging modality to identify patients with overloading or early osteoarthritis.
Key Points
•
Meniscal degeneration and tears correlate significantly with increased BTU using SPECT/CT.
•
Medial meniscus extrusion is associated with an increased BTU in SPECT/CT.
•
SPECT/CT allows detection of overloading and early osteoarthritis.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>29789912</pmid><doi>10.1007/s00330-018-5466-3</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0003-1560-0247</orcidid></addata></record> |
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| ispartof | European radiology, 2018-11, Vol.28 (11), p.4696-4704 |
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| language | eng |
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| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Adult Aged Arthralgia - diagnosis Arthralgia - etiology Arthralgia - metabolism Arthritis Biocompatibility Biomedical materials Cartilage Cartilage diseases Computed tomography Correlation Degeneration Diagnostic Radiology Extrusion Female Femur Follow-Up Studies Humans Imaging Injuries Internal Medicine Interventional Radiology Knee Knee Joint - diagnostic imaging Knee Joint - metabolism Lesions Magnetic resonance imaging Magnetic Resonance Imaging - methods Male Medicine Medicine & Public Health Menisci, Tibial - diagnostic imaging Menisci, Tibial - metabolism Meniscus Middle Aged Musculoskeletal Neuroradiology Osteoarthritis Osteoarthritis, Knee - complications Osteoarthritis, Knee - diagnosis Osteoarthritis, Knee - metabolism Overloading Patients Positron Emission Tomography Computed Tomography - methods Prospective Studies Radiology Radiopharmaceuticals - pharmacokinetics ROC Curve Single photon emission computed tomography Statistical analysis Subchondral bone Surgery Tearing Technetium Tc 99m Medronate - analogs & derivatives Technetium Tc 99m Medronate - pharmacokinetics Ultrasound Young Adult |
| title | Meniscal pathologies on MRI correlate with increased bone tracer uptake in SPECT/CT |
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