Goal-directed perfusion to reduce acute kidney injury: A randomized trial

To determine whether a goal-directed perfusion (GDP) strategy aimed at maintaining oxygen delivery (DO2) at ≥280 mL·min−1·m−2 reduces the incidence of acute kidney injury (AKI). This multicenter randomized trial enrolled a total of 350 patients undergoing cardiac surgery in 9 institutions. Patients...

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Veröffentlicht in:	The Journal of thoracic and cardiovascular surgery 2018-11, Vol.156 (5), p.1918-1927.e2
Hauptverfasser:	Ranucci, Marco, Johnson, Ian, Willcox, Timothy, Baker, Robert A., Boer, Christa, Baumann, Andreas, Justison, George A., de Somer, Filip, Exton, Paul, Agarwal, Seema, Parke, Rachael, Newland, Richard F., Haumann, Renard G., Buchwald, Dirk, Weitzel, Nathaen, Venkateswaran, Rajamiyer, Ambrogi, Federico, Pistuddi, Valeria
Format:	Artikel
Sprache:	eng
Schlagworte:	acute kidney injury Acute Kidney Injury - diagnosis Acute Kidney Injury - mortality Acute Kidney Injury - prevention & control Aged Australia cardiac surgery Cardiac Surgical Procedures - adverse effects Cardiac Surgical Procedures - methods Cardiac Surgical Procedures - mortality cardiopulmonary bypass Cardiopulmonary Bypass - adverse effects Cardiopulmonary Bypass - methods Cardiopulmonary Bypass - mortality Erythrocyte Transfusion Europe Female Hospital Mortality Humans Incidence Intensive Care Units Length of Stay Male Middle Aged New Zealand oxygen delivery Perfusion - adverse effects Perfusion - methods Perfusion - mortality Protective Factors Risk Factors Time Factors Treatment Outcome United States
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